HR: 0800h
AN: P51D-0963 [Abstracts]
TI: Astrobiological Molecularly Imprinted Polymer Sensors
AU: * Izenberg, N R
EM: noam.izenberg@jhuapl.edu
AF: The Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, MD 20723
United States
AU: Murray, G M
EM: george.murray@jhuapl.edu
AF: The Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, MD 20723
United States
AU: Van Houten, K A
EM: Kelly.Van.Houten@jhuapl.edu
AF: The Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, MD 20723
United States
AU: Hofstra, A A
EM: Amy.Hofstra@jhuapl.edu
AF: The Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, MD 20723
United States
AB:
Development of Molecularly Imprinted Polymer (MIP) sensors for astrobiology is intended to provide a new class of
microlaboratory sensors compatible with other life or biomarker detection. Molecular imprinting is a process for making
selective binding sites in synthetic polymers. The process may be approached by designing the recognition site or by simply
choosing monomers that may have favorable interactions with the imprinting molecule. We are working to apply this
methodology to astrobiology for development of a reliable, low cost, low mass, low power consumption sensor technology for
quantitative in-situ analysis of biochemistry, biomarkers, and other indicators of astrobiological importance. Specific goals
of the project are: 1) To develop a general methodology and specific methods for MIP-based sensor construction. The overall
methodology will guide procedures for design and testing of any desired sensor. Specific methods will be applied to key
families and specific species of astrobiological interest, i.e., alkanes (and Polycyclic aromatic hydrocarbons - PAHs), amino
acids, steroids, and hopanes; 2) To construct and characterize the general family and specific species sensors. We will test
for accuracy, precision, interferences, and limitations of the sensor against blanks, standards, and known terrestrial
biological environment samples. Additional testing will determine sturdiness and longevity of sensors after exposure to
transit conditions (launch and space environment), and at potential target environments (pressure, temperature, pH, etc.);
and 3) To construct and demonstrate the combination of multiple sensors into a viable prototype instrument, and roadmap the
expansion of potential instrument capabilities and exploration of the ultimate environmental limitations of the technology,
and the necessary changes and additions to create a mission-ready instrument. Initial work has resulted successful detection
of aqueous alanine (D and L) with simple MIP sensors, and we will present results for other amino acid detector
methodologies.
DE: 0452 Instruments and techniques
DE: 5200 PLANETARY SCIENCES: ASTROBIOLOGY
DE: 5494 Instruments and techniques
DE: 6094 Instruments and techniques
SC: Planetary Sciences [P]
MN: Fall Meeting 2005