HR: 0800h
AN: H21A-1000 [Abstracts]
TI: Evaluation of the Factors that Control the Time-Dependent
Inactivation Rate Coefficients of Bacteriophage MS2 and PRD1
AU: * Anders, R
EM: randers@usgs.gov
AF: U. S. Geological Survey, 5735 Kearny Villa Rd. Ste. O, San Diego, CA 92123
United States
AU: * Anders, R
EM: randers@usgs.gov
AF: Department of Civil and Environmental Engineering, University of California, Irvine, CA 92697
United States
AU: Chrysikopoulos, C V
EM: costas@eng.uci.edu
AF: Department of Civil and Environmental Engineering, University of California, Irvine, CA 92697
United States
AU: Chrysikopoulos, C V
EM: costas@eng.uci.edu
AF: Department of Civil Engineering, University of Patras, Rio, 26500
Greece
AB:
Batch experiments were conducted under both static and dynamic conditions to study the effects of
temperature and the presence of sand on the inactivation process of viruses. The male--specific RNA coliphage, MS2, and the
{\sl Salmonella typhimurium} phage, PRD1, were used as model viruses for this study. Over 100 oven--baked borosilicate glass
bottles with or without Monterey sand were filled with a low--ionic--strength phosphate buffered saline solution containing
both bacteriophage and incubated at temperatures of 4$^\circ$, 15$^\circ$, or 25$^\circ$C.
The results of the batch experiments indicate that the inactivation process can
be represented by a pseudo first-order expression with time--dependent rate
coefficients. A combination of high temperature and the presence of sand appears to produce the greatest disruption to the
surrounding protein coat of MS2. However, for PRD1, the lower activation
energies derived from Arrhenius plots indicate a weaker dependence of the inactivation rate on temperature.
Furthermore, the presence of an air--liquid--solid interface in the dynamic batch experiment containing sand produces the
greatest damage to specific viral components of PRD1 that are required for infection. These results indicate the use of
thermodynamic parameters based on the pseudo first--order inactivation expression allows better prediction of the
inactivation of viruses in the environment.
DE: 1829 Groundwater hydrology
DE: 1831 Groundwater quality
DE: 1832 Groundwater transport
SC: Hydrology [H]
MN: 2004 AGU Fall Meeting